FH antibody (AA 44-510)

Catalog No. ABIN5542251

The Mouse Monoclonal anti-FH antibody has been validated for WB and EIA. It is suitable to detect FH in samples from Human.

Quick Overview for FH antibody (AA 44-510) (ABIN5542251)

Target: FH (Fumarate Hydratase (FH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FH antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT3F6

Product Details anti-FH Antibody

Binding Specificity: AA 44-510

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human Fumarase (44-510aa) purified from E. coli.

Isotype: IgG2a

Application Details

Application Notes: The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for FH

Target: FH (Fumarate Hydratase (FH))

Alternative Name: fumarase

Background: Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-termil extended mitochondrial form. The N-termil extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.

UniProt: P07954